Buy Aricept Online

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Aricept (donepezil)

If you need to buy aricept, read common information about the drug.
Clinico-pharmacological group.
Selective inhibitor of acetylcholinesterase in the brain. Drug for the treatment of Alzheimer's disease.
Pharmacological action.
Aricept or aricept generic -Selective and reversible inhibitor of acetylcholinesterase, which is the predominant type of cholinesterase in the brain. Donepezil inhibits this enzyme is more than 1000 times stronger than butyrylcholinesterase, contained mainly outside the CNS.
After a single dose of Aricept in doses of 5 mg or 10 mg the degree of suppression of acetylcholinesterase activity measured in erythrocyte membranes after taking the drug, was respectively 63.6% and 77.3%.
Cmax of aricept (donepezil) in plasma is reached after about 3-4 hours after ingestion. Plasma concentrations increased in proportion to dose. T1 / 2 from plasma is approximately 70 hours.
Food intake has no effect on the absorption of aricept or aricept generic.
Donepezil approximately 95% bound to plasma proteins. It is assumed that donepezil and / or its metabolites may persist in the body longer than 10 days.
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Donepezil is metabolized in the liver. Information about the intrahepatic recycling of donepezil and / or products of its metabolism is not available.
Aricept or aricept generic is displayed, as well as its metabolites, mainly in the urine: 79% of the dose found in urine and 21% - in the feces. In the urine predominantly found donepezil.

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Indications.
Symptomatic treatment of Alzheimer's type dementia, mild or moderate severity.
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Dosage. Adults (including elderly patients) the drug is administered in an initial dose of aricept 5 mg 1 time / day. Admission to the initial dose is continued for at least 4-6 weeks to reach equilibrium concentrations of donepezil and determine the clinical effect of early therapy. After 1 month dose of Aricept can be increased to 10 mg / day, which is the maximum recommended daily dose.
Supportive therapy can continue for as long as the therapeutic effect exists , which should be regularly assessed.
If hepatic dysfunction and kidney failure dose adjustment is not required.

Before buy aricept, look side effects of aricept.
Side effects.
From the digestive system: frequent (> 5%) - diarrhea, nausea, and vomiting.
From the central and peripheral nervous system: frequent (> 5%) - fatigue, insomnia, muscle cramps.
Cardio-vascular system: rarely - syncope, bradycardia, sinoatrial and AV-block.
Other: rarely - a slight increase in the concentration of muscle creatine kinase in serum.
In controlled clinical studies, patients were also observed:
CNS: headache, dizziness, hallucinations, anxiety, aggressive behavior, seizures.
Part of the digestive system: dyspepsia, hepatitis, gastric ulcers and duodenal ulcers and bleeding from the gastrointestinal tract.
Other: Pain various locations, accidents, bad cold.

You have to buy aricept online? Read contraindications.
Contraindications.
Hypersensitivity to donepezil hydrochloride, the other components of the drug, as well as to derivatives of piperidine.

Pregnancy and breastfeeding. Look this part if you want aricept online.
Controlled trials of Aricept during pregnancy and lactation was not conducted. There is no information about the derivation of donepezil in human milk. The drug should be prescribed to pregnant women only if the expected benefits of treatment exceed the possible risk to the fetus.

Use in Pediatrics.
Safety and efficacy of Aricept or aricept generic for children has not been studied, and the drug not advisable to appoint these patients.

Overdose.
Symptoms: severe nausea, vomiting, excessive salivation, sweating, bradycardia.
Treatment: symptomatic therapy.

Storage.
The drug should be stored out of reach of children at a temperature not more than 30 ° C. Shelf life - 3 years.

Product form.
Pills:
aricept 10 mg (Normal Dosage)
aricept 5 mg (Low dosage).

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